Scientists Are One Step Closer To Developing Vaccines Against Aggressive Cancers
Humans have learned to fight off illnesses in many ways. Some solutions are as simple as eating the right food and resting for a little while. Other times an illness may require hospitalization and antibiotics. Cancer, one of the biggest illness, may now have to contend with humanity’s newest hope in fighting it off.
Researchers have found a new way to fight off cancerous tumors in the human body. Using lab mice afflicted with melanoma, a predetermined number of rodents were given an experimental immunity booster, Diprovocim, in conjunction with a cancer fight drug to test the results.
In the study, eight mice were given the anti-cancer therapy anti-PD-L1. Eight others received the vaccine combined with alternative alum, and eight more were given the Diprovocim plus the cancer vaccine. Survival rates varied among each group of rodents.
“This co-therapy produced a complete response-a curative response-in the treatment of melanoma,” said Professor Dr. Dale Boger, co-lead on the study.
The ‘co-therapy,’ as the researchers referred to it, works by boosting the body’s own immune system and attracting cancer-fighting cells to tumor sites like a magnet.
“Just as a vaccine can train the body to fight off external pathogens, this vaccine trains the immune system to go after a tumor,” Boger explained further.
Because Diprovocim is a molecule that is both easy to create and work with, it gives researchers hope it might be used to treat other ailments.
In the mice that were given both the cancer-fighting drug and Diprovocim, the creation of leukocytes (cancer-fighting cells) by the immune system was observed.
Attempts were made to reintroduce melanoma to the rodents that appeared to be cured, but according to Professor Boger, “The animal was already vaccinated against it.”
There is great potential in this therapy and hopefully, it can lead to the cure for many forms of cancer.